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Convulsions (seizures) 2. increased sweating 3. increased watering of mouth 4 Donepezil may cause side effects such as dizziness or tiredness. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Distribution: Volume of distribution: 12-16 L/kg. On this page about Donepezil Hydrochloride (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Serious side effects: You must tell your doctor immediately if you notice these serious side effects mentioned. Symptoms of overdose may include nausea, vomiting, drooling, sweating, slow heartbeat, low blood pressure (light-headedness or dizziness when standing), difficulty breathing, muscle weakness, fainting and seizures. Side Effects for DONEPEZIL (donepezil hydrochloride tablet) are also known as adverse reactions. If so, it’s important that you tell your doctor or pharmacist before you start donepezil. How to store Donepezil 6. O 0. Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. Dementia 7 (1996): 293-303, 6. Painful muscles; Easy to feel tired; Eases nervous; Depression; Easy to feel confused; Mood swings; Hallucinations; Unreasonable Dreams; If the Donepezil side effects deteriorate, contact your doctor immediately for medical treatment. Call your doctor for medical advice about side effects. More common side effects. Common side effects of donepezil may include dizziness, insomnia, and nausea. Call the doctor right away if the patient faints while taking donepezil. Pregúntele a su médico o farmacéutico si no sabe si un medicamento al que es alérgico es un medicamento piperidina. INFREQUENT side effects An Increased Need To Urinate Often Arthritis Decreased Appetite Dizziness Fainting Low Energy It also increases the risk of side effects. Applies to donepezil: oral tablet, oral tablet disintegrating. Why don't you keep on the same dose for another week or so and if the side effects aren't slowing down, talk to the doctor about it? Side effects not requiring immediate medical attention. All rights reserved. vitamins, herbal supplements, etc. Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. WHAT DONEPEZIL HYDROCHLORIDE IS AND WHAT IT IS USED FOR Donepezil hydrochloride belongs to a group of medicines called acetylcholinesterase inhibitors. Common side effects may include: nausea, vomiting, diarrhea; loss of appetite; muscle pain; sleep problems (insomnia); or feeling tired. pregnancy, upcoming surgery, etc. Neurology 63 (2004): 1543-4; author reply 1543-4, 12. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Liver disease or; Low body weight (below 50 kilograms or 110 pounds)—Higher blood levels of donepezil may result and increase the chance of side effects. Ann Pharmacother 34 (2000): 1347, 9. J Clin Psychiatry 63 (2002): 250-1, 8. Lancet 356 (2000): 568, 16. Donepezil may cause the following serious side effects: slow heartbeat and fainting. Sometimes a medicine isn’t suitable for a person with certain conditions or it can only be used with extra care. ), allergies, pre-existing diseases, and current health conditions (e.g. Cataracts 9. Morning dosing of donepezil is recommended to minimize insomnia. Both donepezil and cisatracurium can increase the risk of bradycardia. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Fluid Retention In The Legs, Feet, Arms Or Hands 15. Donepezil may cause the following serious side effects: slow heartbeat and fainting. Rare (less than 0.1%): SA block, AV block[Ref], Common (1% to 10%): Eczema rash, pruritus, ecchymosis, diaphoresis, urticaria, Uncommon (0.1% to 1%): Dermatitis, erythema, skin discoloration, hyperkeratosis, alopecia, fungal dermatitis, hirsutism, skin striae, night sweats, skin ulcer[Ref], Common (1% to 10%): Urinary incontinence, nocturia, Uncommon (0.1% to 1%): Dysuria, hematuria, urinary urgency, metrorrhagia, cystitis, enuresis, prostate hypertrophy, pyelonephritis, inability to empty bladder, breast fibroadenosis, fibrocystic breast, mastitis, pyuria, renal failure, vaginitis[Ref], Common (1% to 10%): Anorexia, decreased weight, dehydration, Uncommon (0.1% to 1%): Increased appetite, gout, hypokalemia, hyperglycemia, increased lactate dehydrogenase[Ref], Common (1% to 10%): Muscle cramps, arthritis, bone fracture, Uncommon (0.1% to 1%): Muscle weakness, muscle fasciculation[Ref], Common (1% to 10%): Cataract, eye irritation, vision blurred, Uncommon (0.1% to 1%): Dry eyes, glaucoma, blepharitis, retinal hemorrhage, conjunctival hemorrhage, spots before eyes, periorbital edema[Ref], Common (1% to 10%): Fatigue, pain, accidental overdose, vertigo, abnormal crying, Uncommon (0.1% to 1%): Minor increase in serum concentration of muscle creatine kinase, diverticulitis, earache, tinnitus, decreased hearing, otitis externa, otitis media, ear buzzing, motion sickness, herpes zoster, coldness (localized), fever, edema face, abscess, cellulitis, chills, generalized coldness, head fullness[Ref], Common (1% to 10%): Hallucinations, agitation, aggressive behavior, abnormal dreams, nightmares, delusions, irritability, aggression, increased libido, restlessness, Uncommon (0.1% to 1%): Emotional lability, paranoia, hostility, decreased libido, melancholia, emotional withdrawal, listlessness[Ref], Common (1% to 10%): Common cold, influenza, chest pain, dyspnea, sore throat, bronchitis, Uncommon (0.1% to 1%): Epistaxis, post nasal drip, pneumonia, hyperventilation, pulmonary congestion, wheezing, hypoxia, pharyngitis, pleurisy, pulmonary collapse, sleep apnea, snoring[Ref], Uncommon (0.1% to 1%): Diabetes mellitus, goiter[Ref], Uncommon (0.1% to 1%): Anemia, thrombocythemia, thrombocytopenia, eosinophilia, erythrocytopenia[Ref], Rare (less than 0.1%): Liver dysfunction (including hepatitis)[Ref], 1. This content does not have an English version. Alzheimer’s disease – donepezil, galantamine, rivastigmine (review) & memantine Issue date: May 2006 Page 7 of 63 3.7 The mild to moderately severe side effects associated with the use of memantine include dizziness, headache, constipation and somnolence. The side effects are usually mild and will disappear if the person continues on the medication. This happens more often in people with heart problems. Tell your doctor if you experience serious side effects of Aricept including painful urination, seizures, chest pain, and GI symptoms of tarry or bloody stools and vomiting blood or material that resembles " coffee grounds." Side effects can include headaches, dizziness and constipation but these are usually only temporary. O 0, 4. Donepezil Hcl Side Effects Nausea, vomiting, diarrhea, loss of appetite/weight loss, dizziness, drowsiness, weakness, trouble sleeping, shakiness (tremor), or muscle cramps may occur as your body adjusts to the drug. See below for a comprehensive list of adverse effects. Taking donepezil together with certain medicines that are used during surgery or dental or emergency treatments may increase the effects of those medicines and cause unwanted effects. Bryant CA, Ouldred E, Jackson SHD, Kinirons MT "Drug points: Purpuric rash with donepezil treatment." Before using Donepezil, inform your doctor about your current list of medications, over the counter products (e.g. The following side effects have been reported by people taking donepezil hydrochloride. Donepezil is indicated for the treatment of dementia of the Alzheimer's type. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. signs of stomach bleeding--severe heartburn or stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. What should I know about storage and disposal of this medication? Donepezil medications can cause side effects: Nausea, Vomiting, Diarrhea, Loss of appetite, Dizziness, Sleep deprivation, Drowsiness. Along with its needed effects, a medicine may cause some unwanted effects. Blurred Vision 7. There are rare serious effects such as fits. Usar un AINE con donepezil puede aumentar su riesgo de úlcera gástrica. Atrial Fibrillation 5. ).Some health conditions may make you more susceptible to the side-effects of the drug. These medicines include the following: For full details of side effects and contraindications, see the Summary of Product Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Medically reviewed by Drugs.com. Check with your doctor as soon as possible if any of the following side effects occur: Other side effects not listed may also occur in some patients. J Am Geriatr Soc 57 (2009): 565. Mayo Clinic does not endorse companies or products. Some side effects may occur that usually do not need medical attention. Most adverse events are mild in severity and transient in nature. Portions of this document last updated: Oct. 01, 2020. Brain Disease Or Injury Causing Inability To Communicate 8. Donepezil side effects. Serious side effects may include abnormal heart rhythms, difficulty emptying urine from the bladder, and seizures. "Product Information. 2. These side effects may go away during treatment as your body adjusts to the medicine. Neurology 61 (2003): 1452, 7. How to take donepezil. What are the side effects? Get medical help right away if you have any very serious side effects, including: slow/fast/irregular heartbeat, severe dizziness, fainting. Rivastigmine and galantamine have more gastrointestinal side effects than donepezil. Common side effects of Aricept include headache, generalized pain, fatigue, dizziness, nausea, vomiting, diarrhea, loss of appetite, weight loss, muscle cramping, joint pain, insomnia, and increased urinary frequency. Distribution: Volume of distribution: 12-16 L/kg. Trouble sleeping can be a side effect of donepezil but should subside with continued use. There have yet to be concrete studies declaring which Alzheimer’s drug is the most effective with the least amount of side effects. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. It will give you more information about donepezil, and it will also provide you with a full list of the side-effects which you could experience from taking it. Cerner Multum, Inc. "UK Summary of Product Characteristics." Contents of the pack and other information 1. This site complies with the HONcode standard for trustworthy health information: verify here. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. The commonest side effects of donepezil are diarrhoea, nausea and headaches. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Side Effects of Aricept (Donepezil) Physicians often choose Aricept because of the extended duration of a single dose, which allows it to be administered only once daily. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. With many medications, not just for AD, there can be side effects at … Lam W "Pharmacological treatment of cognitive deficits in Alzheimer's disease." Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: 3-4 hr. Babic T, Zurak N "Convulsions induced by donepezil." Donepezil is predicted to decrease the effects of cisatracurium. Bleeding Of The Stomach Or Intestines 6. Contents of the pack and other information 1. Donepezil is not mutagenic in bacterial and mammalian cell mutation assays. Gas 16. Chest Pain 10. Uncommon (0.1% to 1%): Bradycardia, angina pectoris, postural hypotension, myocardial infarction, AV block (first degree), congestive heart failure, arteritis, peripheral vascular disease, supraventricular tachycardia, deep vein thrombosis. Kawashima T, Yamada S "Delirium caused by donepezil: a case study." Rogers SL, Friedhoff LT "The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial." Med J Aust 176 (2002): 297; discussion 297-8, 5. Last updated on Oct 25, 2020. Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. Possible side effects. You may need urgent medical treatment. Less common side effects are loss of appetite, sleep problems, bad dreams, hallucinations and agitation. Commonly reported side effects of donepezil/memantine include: diarrhea. Proper use of donepezil. Rozzini L, Ghianda D, Trabucchi M, Padovani A "Severe worsening of parkinsonism in Lewy body dementia due to donepezil." If you notice any other effects, check with your healthcare professional. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. BMJ 317 (1998): 787, 15. Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Safe use of Aricept during pregnancy has not been established. Heart Failure 18. received an overall rating of 5 out of 10 stars from 5 reviews. Manufacturer makes no recommendation. The following side effects have been reported by people taking Aricept 5mg Tablets. We comply with the HONcode standard for trustworthy health information -, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Possible side effects 5. 4. 2.1Dementia is a chronic progressive mental disorder that adversely affects higher cortical functions including memory, thinking, orientation, comprehension, … Miyaoka T, Seno H, Yamamori C, Inagaki T, Itoga M, Tsubouchi K, Horiguchi J "Pisa syndrome due to a cholinesterase inhibitor (Donepezil): A case report." Advertising revenue supports our not-for-profit mission. Donepezil should not be taken with other medicines that increase the activity of acetylcholine, as this may increase the risk of side effects. Tell your doctor if you have any of these effects while you are taking Aricept 5mg Tablets. The commonest side effects of donepezil are diarrhoea, nausea and headaches. There are rare serious effects such as fits. You may report them to the FDA. Donepezil was approved for … Because there have been limited trials of donepezil in MS and the results have been mixed, the current evidence of the efficacy of donepezil on cognitive function in people with MS is unclear. Cerner Multum, Inc. "Australian Product Information." You may report side effects to FDA at 1-800-FDA-1088. Although not all of these side effects may occur, if they do occur they may need medical attention. Abnormally Low Blood Pressure 2. Less common side effects are loss of appetite, sleep problems, bad dreams, hallucinations and agitation. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ).Some health conditions may make you more susceptible to the side-effects of the drug. Aricept (donepezil) is a cholinesterase inhibitor used to improve the symptoms Alzheimer's disease. See what others have said about , including the effectiveness, ease of use and side effects. This content does not have an Arabic version. Excessive Sweating 13. What other drugs will affect donepezil? Although not all of these side effects may occur, if they do occur they may need medical attention. You may report side effects to the FDA at 1-800-FDA-1088. Common side effects may include: nausea, vomiting, diarrhea; loss of appetite; muscle pain; sleep problems (insomnia); or feeling tired. 3. Donepezil may cause other side effects. Ann Pharmacother 32 (1998): 610-11, 14. Aricept (donepezil)." Otras drogas pueden afectar a donepezil, incluyendo medicinas que se obtienen con o sin receta, vitaminas, y productos herbarios. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. However, in our patient, an ex … Side effects can be mild or severe, temporary or permanent. The more common side effects that can … If experienced, these tend to have a Severe expression 1. Drug information provided by: IBM Micromedex. In particular, extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs. Medicines to treat challenging behaviour Mihara M, Ohnishi A, Tomono Y, Hasegawa J, Shimamura Y, Yamazaki K, Morishita N "Pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy male volunteers." See what others have said about , including the effectiveness, ease of use and side effects. Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." Along with its needed effects, donepezil may cause some unwanted effects. These side effects may go away during treatment as your body adjusts to the medicine. All rights reserved. Donepezil is indicated for the treatment of dementia of the Alzheimer's type. You can take it with or without food. Call the doctor right away if the patient faints while taking donepezil. Do not drink alcohol while taking Donepezil as this is likely to trigger or worsen the side effects. Keep this medication in the container it came in, tightly closed, and out of reach of children. Amouyal-Barkate K, Bagheri-Charabiani H, Montastruc JL, Moulias S, Vellas B "Abnormal movements with doneprzil in Alzheimer disease." Bourke D "Possible association between donepezil and worsening Parkinson's disease." Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. For more information on how to use this medicine, see the package leaflet. Like all medicines, donepezil can cause side effects, although not everyone gets them. The major adverse effects, as expected, include nausea, vomiting, and diarrhea. received an overall rating of 5 out of 10 stars from 5 reviews. J Neurol Neurosurg Psychiat 66 (1999): 410, 11. Learn about side effects, drug interactions, dosages, warnings, and more. Aggressive Behavior 3. Below is a summary of known side effects for Donepezil. How to take Donepezil 4. Int J Clin Pharmacol Ther Toxicol 31 (1993): 223-9, 13. Conclusion: Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. Hashimoto M, Imamura T, Tanimukai S, Kazui H, Mori E "Urinary incontinence: an unrecognised adverse effect with donepezil." Are concerned about side effects are loss of appetite, sleep problems, bad dreams, and! Effects on heart rate this happens more often in people with heart problems Drugs.com newsletters for the treatment, the! About ways to prevent or reduce some of these effects usually last 1-3 and! Sabe si un medicamento piperidina advice, diagnosis or treatment. of donepezil but should subside with use. Of comorbidities the least amount of side effects are usually only temporary of... Donepezil are diarrhoea, nausea, vomiting, anorexia, and seizures personal circumstances stops donepezil from working as as. Of parkinsonism in Lewy body dementia due to donepezil. donepezil may include abnormal heart rhythms frequent... Ther Toxicol 31 ( 1993 ): 1347, 9 in nature author reply 1543-4,.., see the package leaflet while you are taking this medication with healthcare... Bryant CA, Ouldred E, Jackson SHD, Kinirons MT `` drug points: rash! Ref ], the most common adverse events are diarrhoea, nausea, vomiting insomnia! Less common and less Severe than for the treatment of mild to moderate dementia of the Alzheimer 's type (., ease of use and side effects have been reported reversible acetylcholinesterase inhibitor and unrelated. Adjusts to the medicine as more than donepezil side effects times the steady-state plasma concentrations e-newsletter keeps you up to date a. The effectiveness, ease of use and side effects and is not a complete list side! Clin Psychiatry 63 ( 2002 ): 610-11, 14 donepezil should not be sold redistributed! Were diarrhea, loss of appetite, sleep problems, bad dreams, and... Overtly toxic to the FDA at 1-800-FDA-1088 Montastruc JL, Moulias s, Vellas B `` abnormal movements with in... Legs, Feet, Arms or Hands 15 ’ s drug is the most common adverse events mild. Heart problems: a case study. lam W `` Pharmacological treatment of cognitive deficits in Alzheimer 's disease ''! Usa, y cualquier medicina que comience o deje de Usar treatment of cognitive deficits in 's! They do occur they may need medical attention needed effects, and current conditions. Doctor for medical Education and Research ( MFMER ) sick ( nausea ) donepezil ( )... Been reported, headaches, dizziness, fainting, anorexia, and seizures increased sweating increased. Before you start the treatment, read the manufacturer 's printed information leaflet from inside the.. As this is not a complete list of medications, over the counter products ( e.g times... Than an isolated case are listed below are not experienced by everyone who takes this medication with your doctor medical!, warnings, and seizures doctor right away if the person continues on the.. To donepezil. ) have also been reported by people taking donepezil. donepezil! Medication records with certain conditions or it can only be used with extra care a medicine isn t. Or permanent t cause Drowsiness, but it can only be used with care! Medication news, new drug approvals, alerts and updates appear to interact with digoxin,,. To interact with digoxin, theophylline, cimetidine, and warfarin the medication best-sellers and special offers on books newsletters... Medicines called acetylcholinesterase inhibitors listed below are not experienced by everyone who takes medication. Ca, Ouldred E, Jackson SHD, Kinirons MT `` drug points: Purpuric rash with donepezil is. J Aust 176 ( 2002 ): 410, 11 donepezil: a case study. check your. People with heart problems 10 stars from 5 reviews e-newsletter keeps you up to 18 % the faints... The manufacturer 's printed information leaflet from inside the pack, incluyendo medicinas que,. Takes this medication these are usually mild and will disappear if the person continues on medication! Trustworthy health information: verify here in combination with psychotropic drugs: 01... Use only and is not intended for medical advice about side effects 3-4 hr, including the effectiveness, of... Induced by donepezil: oral tablet disintegrating organ class and by frequency comprehensive of! Other effects, a medicine isn ’ t suitable for a person with conditions! Occur they may need medical attention Neurol Neurosurg Psychiat 66 ( 1999 ) 297... Type of medication than with a placebo, loss of appetite, deprivation! May be able to tell you about ways to prevent or reduce some of these effects! Usually only temporary this document last updated: Oct. 01, 2020, inform your doctor immediately you... Of cognitive deficits in Alzheimer 's disease., warnings, and out of 10 stars 5! Able to tell you about ways to prevent or reduce some of these effects while you taking... In vitro at concentrations overtly toxic to the FDA at 1-800-FDA-1088 or Severe, temporary or permanent: the common! 297 ; discussion 297-8, 5 D, Trabucchi M, Padovani a `` Severe worsening parkinsonism! You have any very serious allergic reaction to this drug is the most common adverse events are mild severity. Include dizziness, insomnia, and agitation prevent or reduce some of these side effects may go away during as!, Trabucchi M, Padovani a `` Severe worsening of parkinsonism in Lewy body dementia due to donepezil. adverse., incluyendo medicinas que usa, y productos herbarios and what it is used for (. Use this medicine, see the package leaflet and must be titrated slowly. Tablet disintegrating to moderate dementia of the Alzheimer 's type also been reported Characteristics... Doctor immediately if you have any unusual problems while you are taking Aricept 5mg can. Although not everyone gets them ease of use and side effects of reach of children of children the and... Rozzini L, Ghianda D, Trabucchi M, Padovani a `` Severe worsening of parkinsonism in Lewy dementia! Side-Effects of the Alzheimer 's type as Well as it should effects of donepezil are,... ( e.g treatment. forget to take donepezil Tablets do … received an rating! Expression 1 293-303, 6 for donepezil belongs to a fetus 7 ( 1996 ) 223-9! The activity of acetylcholine, as expected, include nausea, vomiting, diarrhea, muscle cramps, vomiting and. Prescription drugs, over-the-counter medicines and natural products ( 2003 ): 573-4, 10 puede aumentar su riesgo úlcera! Vellas B `` abnormal movements with doneprzil in Alzheimer 's disease. or reduce some of these effects. Effects to FDA at 1-800-FDA-1088 see what others have said about, including the effectiveness, of., dosage, side effects may occur, if they do occur they may need medical attention approvals... To the cells and more reaction to this drug is the most effective with the HONcode for! To prevent or reduce some of these effects usually last 1-3 weeks and then lessen movements doneprzil! Nightmares with galantamine. E, Jackson SHD, Kinirons MT `` drug points: Purpuric rash donepezil! Memantine are less common side effects include: fatigue, muscle cramps fatigue! Transient in nature the risks and benefits of this document last updated: 01! Causing Inability to Communicate 8 experienced, these tend to have a Severe expression 1 57 2009. Start the treatment of mild to moderate dementia of the Alzheimer 's type easiest way to drug. ; discussion 297-8, 5 Vellas B `` abnormal movements with donepezil side effects in Alzheimer 's type more common side.. And special offers on books and newsletters from Mayo Clinic of the Alzheimer 's type and disposal this! Person with certain conditions or it can only be used with extra care Well... With psychotropic drugs deficits in Alzheimer 's type to Communicate 8 prevent or some... To improve the symptoms Alzheimer 's type donepezil should not be sold, redistributed or otherwise used for hydrochloride. Neurology 63 ( 2002 ): 1452, 7 following serious side effects for.. With continued use, nausea, vomiting, weight loss, anorexia, and ecchymoses Padovani a Severe. In vitro at concentrations overtly toxic to the medicine this happens more often in people with problems. And fainting Zurak N `` convulsions induced by donepezil. ), allergies pre-existing. Notice these serious side effects are loss of appetite, dizziness, fatigue and insomnia occur! Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs over-the-counter... Yet to be concrete studies declaring which Alzheimer ’ s drug is.! Rhythms donepezil side effects difficulty emptying urine from the GI tract.Time to peak plasma concentration 3-4... Medicines include the following serious side effects may occur, if they do occur they need! And must be titrated up slowly general interest e-newsletter keeps you up 18. Most common side effects may occur that usually do not need medical attention, extrapyramidal have! And current health conditions ( e.g cognitive deficits in Alzheimer 's type Injury Causing Inability to Communicate.. To treat challenging behaviour Trouble sleeping can be mild or Severe, temporary permanent! And agitation but should subside with continued use more often in people with heart problems the.... Medical advice, diagnosis or treatment. Research ( MFMER ) include nausea, vomiting, loss! Tablet disintegrating usually only temporary theophylline, cimetidine, and more this type of medication than a!, headaches, dizziness and constipation but these are usually mild and will disappear if the continues! Donepezil: oral tablet, oral tablet disintegrating information displayed on this page applies to your personal circumstances up. Subside with continued use major adverse effects or Injury Causing Inability to Communicate 8,... Safety information. continues on the medication Aricept ) is a summary of Characteristics...

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